MEF2CARTICLE

Finding the clues for better autism treatments

Medical University of South Carolina (sciencedaily.com) New research sheds light on what might be going wrong in the regulation of genes that govern the brain’s connectivity. The study's intention is to identify new clues to improve treatments for autism. Dr. Christopher W. Cowan used special microphones to listen to mice interact. They speak at ultrasonic frequencies beyond what humans can hear. As a researcher at Harvard Medical School, Christopher W. Cowan, Ph.D., used to watch autistic kids come onto campus to attend a special school.

What’s to come for CRISPR in 2017?

What’s to come for CRISPR in 2017?
In the short time since its discovery, CRISPR has enabled tremendous scientific advances that have caught headlines and spotlight around the world. Today we’re looking to the future to see where CRISPR might go in 2017. Like every other year, it’ll shock and stun us with innovative and cutting-edge advances quicker than we ever thought possible, so this is just a starting point.
In 2017 we believe CRISPR…

CRISPR gene editing tested in a human for the first time

A Chinese group of scientists has become the first to inject a person with edited genes using the revolutionary and still controversial CRISPR-Cas9 technique. Key points: CRISPR-Cas9 can trim away unwanted parts of the genome A protein that slows down the cell's immune response was trimmed out of the DNA The edited DNA was cultivated and injected back into the patient A patient with aggressive lung cancer received the modified cells as part of a clinical trial at the West China Hospital in Chengdu.

Breakthrough for DNA-editing: US team discovers 'holy grail' to fix genes to cure incurable diseases

Scientists have discovered how to edit DNA to repair 'broken genes' to cure incurable diseases - and potentially extend human lifespan. Until now, it has not been possible to alter genes in the brain, heart, liver and eyes - the root of many debilitating illnesses. Since the cells in these vital organs tend not to divide, it is difficult to gain access to make changes. However, researchers at the Salk Institute claim to have landed on 'the holy grail of gene editing', which can delicately and smoothly cut through DNA.

CRISPR/C2c2

You've probably heard of CRISPR - the gene editing tool that essentially lets scientists cut and paste DNA, removing things like HIV and muscular dystrophy from our cells - and now scientists have discovered a way to edit RNA with just as much precision. RNA is DNA's close biological cousin, responsible for translating messages from the nucleus to the rest of the cell, and being able to change it could open up all-new disease-fighting possibilities.

The gene editor CRISPR won’t fully fix sick people anytime soon. Here’s why

This week, scientists will gather in Washington, D.C., for an annual meeting devoted to gene therapy—a long-struggling field that has clawed its way back to respectability with a string of promising results in small clinical trials. Now, many believe the powerful new gene-editing technology known as CRISPR will add to gene therapy’s newfound momentum. But is CRISPR really ready for prime time? Science explores the promise—and peril—of the new technology.

How does CRISPR work?